发明申请
US20090220589A1 TREATMENT, DIAGNOSTIC, AND METHOD FOR DISCOVERING ANTAGONIST USING SPARC SPECIFIC MIRNAS
审中-公开
治疗,诊断和使用SPARC特异性MIRNAS发现ANTAGONIST的方法
- 专利标题: TREATMENT, DIAGNOSTIC, AND METHOD FOR DISCOVERING ANTAGONIST USING SPARC SPECIFIC MIRNAS
- 专利标题(中): 治疗,诊断和使用SPARC特异性MIRNAS发现ANTAGONIST的方法
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申请号: US12395872申请日: 2009-03-02
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公开(公告)号: US20090220589A1公开(公告)日: 2009-09-03
- 发明人: Vuong Trieu , Larn Hwang , Neil Desai
- 申请人: Vuong Trieu , Larn Hwang , Neil Desai
- 申请人地址: US CA Los Angeles
- 专利权人: Abraxis BioScience, LLC
- 当前专利权人: Abraxis BioScience, LLC
- 当前专利权人地址: US CA Los Angeles
- 主分类号: A61K9/127
- IPC分类号: A61K9/127 ; A61K31/7105 ; C07H21/02 ; C12N15/63 ; A61P35/00 ; C12Q1/68 ; C07K2/00
摘要:
miRNAs that regulate human SPARC and methods of use thereof are described. Suitable nucleic acids for use in the methods and compositions described herein include, but are not limited to, pri-miRNA, pre-miRNA, ds miRNA, mature miRNA or fragments of variants thereof that retain the biological activity of the mature miRNA and DNA encoding a pri-miRNA, pre-miRNA, mature miRNA, fragments or variants thereof, or regulatory elements of the miRNA.
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