Systems and methods are disclosed that provide WUSB (wireless universal serial bus) and wireless audio/video interfaces within a single device by integrating a Bluetooth subsystem with a WUSB hub and by providing shared operation between the UWB (ultra wide band) and Bluetooth subsystems. In one embodiment, a system includes both a UWB subsystem and a Bluetooth subsystem that are configured to share one or more operational parameters, such as device pairing information. As such, Bluetooth subsystems and the WUSB subsystems are allowed to cooperate and share information to streamline operation, and this streamlining allows the Bluetooth subsystem to handle isochronous operations, such as audio/video communications, and allows the UWB subsystem to continue to handle USB connected peripheral devices. The disclosed systems with WUSB and wireless audio/video interfaces can also be included as subsystems within other devices, such as display monitors or speaker systems for computer systems.