Invention Application
- Patent Title: Selective Inhibitors of Human Corticosteroid Synthases
- Patent Title (中): 人类皮质类固醇合成酶的选择性抑制剂
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Application No.: US11885605Application Date: 2006-03-02
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Publication No.: US20090221591A1Publication Date: 2009-09-03
- Inventor: Rolf W. Hartmann , Marieke Voets , Ursula Müller-Vieira
- Applicant: Rolf W. Hartmann , Marieke Voets , Ursula Müller-Vieira
- Applicant Address: DE Saarbrucken
- Assignee: Universitat Des Saarlandes
- Current Assignee: Universitat Des Saarlandes
- Current Assignee Address: DE Saarbrucken
- Priority: DE102005009705.7 20050303; DE102005029372.7 20050624
- International Application: PCT/EP2006/060410 WO 20060302
- Main IPC: A61K31/498
- IPC: A61K31/498 ; C07D401/04 ; A61K31/497 ; A61K31/4406 ; C07D213/16 ; A61P3/10
Abstract:
The invention relates to compounds for selectively inhibiting human corticosteroid synthases CYP1 1 B1 and CYP1 1 B2, and to the production and use thereof for treating hypercortisolism, diabetes mellitus, hyperaldosteronism, cardiac insufficiency, myocardial fibrosis, depression, age-related cognitive decline and metabolic syndrome.
Public/Granted literature
- US09271963B2 Selective inhibitors of human corticosteroid synthases Public/Granted day:2016-03-01
Information query
IPC分类:
