发明申请
- 专利标题： OPTICALLY ACTIVE CARBAMATES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS PHARMACEUTICAL INTERMEDIATES
- 专利标题（中）： 光活性碳酸酯，其制备方法及其作为药物中间体的用途
-
申请号： US12096636申请日： 2006-12-08
-
公开(公告)号： US20090221823A1公开(公告)日： 2009-09-03
- 发明人: Tibor Mezei , Eniko Molnar , Peter Trinka , Ferenc Bartha , Zoltan Katona , Gyorgyi Vereckeyne Donath , Kalman Nagy , Laszlo Pongo , Gyula Lukacs , Marta Porcs-Makkay , Zsuzsanna Evinger , Gyula Simig
- 申请人： Tibor Mezei , Eniko Molnar , Peter Trinka , Ferenc Bartha , Zoltan Katona , Gyorgyi Vereckeyne Donath , Kalman Nagy , Laszlo Pongo , Gyula Lukacs , Marta Porcs-Makkay , Zsuzsanna Evinger , Gyula Simig
- 优先权： HUP0501139 20051208
- 国际申请： PCT/HU2006/000109 WO 20061208
- 主分类号： C07D241/04
- IPC分类号： C07D241/04
摘要：
The present invention is related to 1-[(4-chlorophenyl)-phenylmethyl]-4-(2,2,2-trichloroethoxycarbonyl)-piperazine of the Formula (IV) and optically isomers thereof, process for preparation thereof and the use of the compound of the Formula (IV) in the preparation of 1-(4-chlorophenyl)-phenylmethyl-piperazine and optical isomers and salts thereof. 1-(4-chlorophenyl)-phenylmethyl-piperazine and optical isomers thereof are important intermediates in the preparation of non-sedating antihistamine-type active pharmaceutical ingredients.
公开/授权文献
信息查询
