发明申请
- 专利标题： Tumor Necrosis Factor Receptors 6 Alpha & 6 Beta
- 专利标题（中）： 肿瘤坏死因子受体6 Alpha＆6 Beta
-
申请号： US12463301申请日： 2009-05-08
-
公开(公告)号： US20090226456A1公开(公告)日： 2009-09-10
- 发明人: Reiner L. Gentz , Reinhard Ebner , Guo-Liang Yu , Steven M. Ruben , Jian Ni , Ping Feng
- 申请人： Reiner L. Gentz , Reinhard Ebner , Guo-Liang Yu , Steven M. Ruben , Jian Ni , Ping Feng
- 申请人地址： US MD Rockville
- 专利权人： Human Genome Sciences, Inc.
- 当前专利权人： Human Genome Sciences, Inc.
- 当前专利权人地址： US MD Rockville
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C12N15/12 ; C07K14/705 ; C07K16/28 ; C12N15/85 ; C12N5/10 ; C12P21/02 ; A61K31/7088 ; C12N5/16 ; G01N33/566
摘要：
The present invention relates to novel Tumor Necrosis Factor Receptor proteins. In particular, isolated nucleic acid molecules are provided encoding the human TNFR-6α & -6β proteins. TNFR-6α & -6β polypeptides and antibodies that bind TNFR-6α & -6β polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of TNFR-6α & -6β activity. Also provided are diagnostic methods for detecting immune system-related disorders and therapeutic methods for treating immune system-related disorders.
公开/授权文献
- US07709218B2 Tumor necrosis factor receptors 6α and 6β 公开/授权日：2010-05-04
信息查询
