发明申请
- 专利标题： Methods and compositions for immunization against hiv
- 专利标题（中）： 用于免疫接种的方法和组合物
-
申请号： US10570512申请日： 2003-10-17
-
公开(公告)号： US20090227658A1公开(公告)日： 2009-09-10
- 发明人: Yaoxing Huang , David D. Ho , Zhiwei Chen
- 申请人： Yaoxing Huang , David D. Ho , Zhiwei Chen
- 国际申请： PCT/US03/33112 WO 20031017
- 主分类号： A61K31/7088
- IPC分类号： A61K31/7088 ; C12N15/63
摘要：
The present invention relates to nucleic acid and attenuated vaccinia vectors for prophylactic use against HIV infection, as well as methods of eliciting immune responses in subjects susceptible to HIV infection. The prophylactic vaccine regimen of the invention involves immunological priming with an inoculum comprising two novel DNA vectors, followed by boosting with a Modified Vaccinia Ankara (MVA) recombinant viral vector expressing the corresponding HIV proteins.
信息查询
