A method of manufacturing a liquid crystal display device includes steps of preparing first and second substrates, forming alignment films on one surfaces of the first and second substrates, respectively, performing rubbing treatment on the alignment films, screen-printing a seal member on the one surface of the first substrate so as to surround a display area, and stacking the first and second substrates on each other while the first surfaces face to each other, with rubbing directions of the alignment films on the first and second substrates being parallel to each other, and joining the first and second substrates through the seal member by curing the seal member while the first and second substrates are bonded to each other through the seal member. The screen-printing is performed while a squeegee is moved in a direction parallel to the rubbing direction of the alignment film formed on the first substrate.