发明申请
US20090246141A1 HIGHER FATTY ACID TRIESTER AND AMIDE DERIVATIVE HAVING DIETHYLENETRIAMINE-TYPE METAL CHELATE STRUCTURE
失效
具有二乙烯胺型金属螯合物结构的高级脂肪酸三羧酸酯和酰胺衍生物
- 专利标题： HIGHER FATTY ACID TRIESTER AND AMIDE DERIVATIVE HAVING DIETHYLENETRIAMINE-TYPE METAL CHELATE STRUCTURE
- 专利标题（中）： 具有二乙烯胺型金属螯合物结构的高级脂肪酸三羧酸酯和酰胺衍生物
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申请号： US12094862申请日： 2006-12-20
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公开(公告)号： US20090246141A1公开(公告)日： 2009-10-01
- 发明人: Atsushi Hirai , Kazunobu Takahashi , Junji Nishigaki , Kazuhiro Aikawa
- 申请人： Atsushi Hirai , Kazunobu Takahashi , Junji Nishigaki , Kazuhiro Aikawa
- 优先权： JP2005-368056 20051221; JP2006-303863 20061109
- 国际申请： PCT/JP2006/325989 WO 20061220
- 主分类号： A61K49/04
- IPC分类号： A61K49/04 ; C07C229/26 ; C07C229/76
摘要：
A compound having superior solubility and suitable for a liposome contrast medium selective for a lesion such as vascular diseases is provided which is represented by the following general formula (I) wherein R1 to R3 represent an alkyl group or alkenyl group; X1 and X2 represent a single bond, —O—, or —N(Z1)- (Z1 represents hydrogen atom, or an alkyl group); X3 to X6 represent —O—, or —N(Z2)- (Z2 represents hydrogen atom, or an alkyl group); n represents an integer of 1 to 10; and L represents a divalent bridging group constituted by atoms selected from the group consisting of carbon atom, hydrogen atom, oxygen atom, nitrogen atom, fluorine atom and sulfur atom.