An automatic gain control loop disposed in a receiver is adapted to compensate for varying levels of out of band interference sources by adaptively controlling the gain distribution throughout the receive signal path. One or more intermediate received signal strength indicator (RSSI) detectors are used to determine a corresponding intermediate signal level. The output of each RSSI detector is coupled to an associated comparator that compares the intermediate RSSI value against a corresponding threshold. The take over point (TOP) for gain stages is adjusted based in part on the comparator output values. The TOP for each of a plurality of gain stages may be adjusted in discrete steps or continuously.