发明申请
- 专利标题： FUSED QUINOLINE DERIVATIVE AND USE THEREOF
- 专利标题（中）： 熔融喹啉衍生物及其用途
-
申请号： US12476626申请日： 2009-06-02
-
公开(公告)号： US20090258893A1公开(公告)日： 2009-10-15
- 发明人: Masahiro Kajino , Nicholas William Hird , Naoki Tarui , Hiroshi Banno , Yasuhiko Kawano , Nobuhiro Inatomi
- 申请人： Masahiro Kajino , Nicholas William Hird , Naoki Tarui , Hiroshi Banno , Yasuhiko Kawano , Nobuhiro Inatomi
- 申请人地址： JP Osaka
- 专利权人： Takeda Pharmaceutical Company Limited
- 当前专利权人： Takeda Pharmaceutical Company Limited
- 当前专利权人地址： JP Osaka
- 优先权： JP2004-134705 20040428
- 主分类号： A61K31/437
- IPC分类号： A61K31/437 ; C07D471/04 ; A61P1/00
摘要：
The present invention aims at provision of a quinoline derivative having a neurokinin 2 (NK2) receptor antagonistic action and relates to a compound represented by the formula (I) wherein R1 is a hydrogen atom and the like; R2 is a hydrogen atom, a hydrocarbon group optionally having substituent(s) and the like; R3 is unsubstituted (i.e., absence), a hydrogen atom and the like; R4 and R5 are the same or different and each is a hydrogen atom, a hydrocarbon group optionally having substituent(s), and the like; R6 is (cyclic group optionally having substituent(s))-carbonyl, and the like; R7, R8, R9 and R10 are the same or different and each is a hydrogen atom, halogen and the like; or R7 and R8, R8 and R9, and R9 and R10 may form a ring together with the adjacent carbon atoms; n is an integer of 1 to 5; represents unsubstituted (i.e., absence) or a single bond; and represents a single bond or a double bond, or a salt thereof, and the like.
公开/授权文献
- US07943770B2 Fused quinoline derivative and use thereof 公开/授权日：2011-05-17
信息查询
IPC分类:
