发明申请
- 专利标题： GAS-FILLED MICROVESICLES WITH POLYMER-MODIFIED LIPIDS
- 专利标题（中）： 气体填充微胶囊与聚合物修饰的脂肪
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申请号： US12440009申请日： 2007-09-04
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公开(公告)号： US20090263330A1公开(公告)日： 2009-10-22
- 发明人: Stephane Gorgerat , Christian Guillot , Feng Yan
- 申请人： Stephane Gorgerat , Christian Guillot , Feng Yan
- 申请人地址： CH Plan-les-Ouates
- 专利权人： BRACCO RESEARCH SA
- 当前专利权人： BRACCO RESEARCH SA
- 当前专利权人地址： CH Plan-les-Ouates
- 优先权： EP06120109.1 20060905
- 国际申请： PCT/EP2007/059256 WO 20070904
- 主分类号： A61K49/22
- IPC分类号： A61K49/22
摘要：
Image enhancing contrast agents for use in diagnostic and/or therapeutic methods, particularly in the form of gas-filled microvesicles, with enhanced stability. The gas-filled microvesicles are stabilized by a layer of amphiphilic material and comprise from 0.15% to 1.0% by moles of a lipid bearing a hydrophilic polymer. The lipid bearing a hydrophilic polymer is preferably a phospholipid linked to polyethyleneglycol.
公开/授权文献
- US09446156B2 Gas-filled microvesicles with polymer-modified lipids 公开/授权日：2016-09-20
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