发明申请
- 专利标题: ENDOTHELIN RECEPTOR ANTAGONIST DERIVATIVES
- 专利标题(中): 内皮素受体拮抗剂衍生物
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申请号: US12300026申请日: 2007-05-23
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公开(公告)号: US20090263472A1公开(公告)日: 2009-10-22
- 发明人: Nicoletta Almirante , Stefano Biondi , Ennio Ongini
- 申请人: Nicoletta Almirante , Stefano Biondi , Ennio Ongini
- 申请人地址: FR Valbonne
- 专利权人: NICOX S.A.
- 当前专利权人: NICOX S.A.
- 当前专利权人地址: FR Valbonne
- 优先权: EP06114617.1 20060529
- 国际申请: PCT/EP07/55012 WO 20070523
- 主分类号: A61K9/127
- IPC分类号: A61K9/127 ; C07D403/04 ; A61K31/506 ; A61K38/06 ; C07K5/097 ; A61K9/12 ; A61K9/48 ; A61K9/28 ; A61P9/00
摘要:
Endothelin receptor antagonist nitroderivatives of general formula (I): having an improved pharmacological activity compared with their parent compounds. They can be employed for treating or preventing endothelial-related disorders, renal, pulmonary, cardiac and vascular diseases, and inflammatory processes.
公开/授权文献
- US1746053A Safety guard 公开/授权日:1930-02-04