- 专利标题： DIARYLAMINE-CONTAINING COMPOUNDS AND COMPOSITIONS, AND THEIR USE AS MODULATORS OF C-KIT RECEPTORS
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申请号： US12475266申请日： 2009-05-29
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公开(公告)号： US20090264649A1公开(公告)日： 2009-10-22
- 发明人: Valentina Molteni , Xiaolin Li , Donatella Chianelli , Jon Loren , Juliet Nabakka , Xiaodong Liu , Shifeng Pan , Yi Liu , Donald S. Karanewsky , Pascal Furet , Vito Guagnano , Shuli You
- 申请人： Valentina Molteni , Xiaolin Li , Donatella Chianelli , Jon Loren , Juliet Nabakka , Xiaodong Liu , Shifeng Pan , Yi Liu , Donald S. Karanewsky , Pascal Furet , Vito Guagnano , Shuli You
- 申请人地址： BM Hamilton HM LX CH Basel
- 专利权人： IRM LLC,Novartis AG
- 当前专利权人： IRM LLC,Novartis AG
- 当前专利权人地址： BM Hamilton HM LX CH Basel
- 优先权： WOPCTUS2006037820 20060926
- 主分类号： C07D403/12
- IPC分类号： C07D403/12 ; C07D239/42 ; C07D413/12 ; C07D417/12
摘要：
Described herein are compounds that include a diarylamine structural feature. Also described herein are methods for making such compounds, methods for using such compounds to modulate the activity of c-kit receptors, and pharmaceutical compositions and medicaments comprising such compounds. Also described herein are methods of using such compounds, pharmaceutical compositions and medicaments to treat and/or prevent and/or inhibit and/or ameliorate the pathology and/or symptomology diseases or conditions associated with the activity of c-kit receptors.