Balloon catheters, and medical devices including balloon catheters, are provided that comprise a balloon assembly disposed at the distal end of an elongated tubular member. The balloon, when in the inflated state, includes a body fluid lumen that extends longitudinally through the balloon and is open at the proximal end of the balloon and the distal end of the balloon. In some aspects, the outer surface of the balloon is contiguous from the proximal end to the distal end of the balloon when the balloon is inflated. In other aspects, an endoluminal prosthesis, for example, a stent that can optionally include a prosthetic valve, surrounds the balloon assembly and is adjacent to the outer surface of the balloon. In still other aspects, endoluminal prosthesis implant devices are provided that are suitable for implanting an endoluminal prosthesis in a body vessel containing a flowing fluid such as a vessel in the heart, e.g., the left or right ventricle inflow or outflow tracks. The endoluminal prosthesis implant devices include a balloon assembly and an endoluminal prosthesis surrounding the balloon assembly. The balloon assembly is configured to permit a fluid to pass from the first end of the balloon to the second end of the balloon when the balloon is in an inflated state. In some embodiments of all of these aspects, the balloon is configured to prevent a fluid from passing from the second end of the balloon to the first end of the balloon when the balloon is in an inflated state. In some embodiments, for example, the body fluid lumen includes a body fluid lumen valve moveable between a first position and a second position. The body fluid lumen valve occludes the body fluid lumen to a greater extent in the first position than in the second position. In some embodiments, the body fluid lumen valve substantially prevents a fluid from flowing through the body fluid lumen in a first direction. Certain aspects and/or embodiments of the balloon catheters, and medical devices including balloon catheters, may allow for the deployment of an endoluminal prosthetic valve (e.g., a heart valve), while the native valve can continue to function uninterrupted under its native load and flow.