发明申请
- 专利标题： Cell Death Inhibitor
- 专利标题（中）： 细胞死亡抑制剂
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申请号： US12442091申请日： 2007-09-21
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公开(公告)号： US20090270326A1公开(公告)日： 2009-10-29
- 发明人: Haruhide Kimura
- 申请人： Haruhide Kimura
- 申请人地址： JP Chuo-ku, Osaka-shi
- 专利权人： Takeda Pharmaceutical Company Limited
- 当前专利权人： Takeda Pharmaceutical Company Limited
- 当前专利权人地址： JP Chuo-ku, Osaka-shi
- 优先权： JP2006-257487 20060922
- 国际申请： PCT/JP2007/069141 WO 20070921
- 主分类号： A61K38/16
- IPC分类号： A61K38/16 ; C12N5/02 ; A61K31/5415
摘要：
The present invention relates to an antioxidant response element (ARE) activator comprising a macrophage migration inhibitory factor (MIF) or a modified form thereof, an ARE activator comprising a combination of MIF or a modified form thereof and a substance capable of binding to MIF, and so on. These ARE activators are useful as safe and excellent cell death inhibitors, such as agents for the prevention/treatment of cardiovascular diseases, bone/joint diseases, infectious diseases, inflammatory diseases, renal diseases, central nervous system diseases, cancer or diabetes.
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