发明申请
- 专利标题： 2,3-DIHYDRO-IMINOISOINDOLE DERIVATIVES
- 专利标题（中）： 2,3-二氢 - 咪唑啉衍生物
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申请号： US12234116申请日： 2008-09-19
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公开(公告)号： US20090270433A1公开(公告)日： 2009-10-29
- 发明人: Richard Clark , Atsushi Takemura , Nobuhisa Watanabe , Osamu Asano , Tadashi Nagakura , Kimlyo Tabata
- 申请人： Richard Clark , Atsushi Takemura , Nobuhisa Watanabe , Osamu Asano , Tadashi Nagakura , Kimlyo Tabata
- 申请人地址： JP Tokyo
- 专利权人： Eisai R&D Management Co., Ltd.
- 当前专利权人： Eisai R&D Management Co., Ltd.
- 当前专利权人地址： JP Tokyo
- 优先权： JP2007-245988 20070921
- 主分类号： A61K31/506
- IPC分类号： A61K31/506 ; C07D413/14 ; C07D405/14 ; A61K31/427
摘要：
A compound represented by the following general formula (1), or a salt thereof has serine protease inhibiting activity, and particularly excellent inhibiting activity against clotting factor VIIa. This compound or a salt thereof is useful as therapeutic and/or prophylactic agents for diseases associated with thrombus formation. [wherein R1 represents hydrogen, R2 represents optionally substituted phenyl, etc., R3 represents optionally substituted C6-10 aryl, etc.]
公开/授权文献
- US07807690B2 2,3-dihydro-iminoisoindole derivatives 公开/授权日：2010-10-05