发明申请
- 专利标题: IN VIVO IMAGING AGENTS FOR MET RECEPTOR TYROSINE KINASE
- 专利标题(中): 用于MET受体酪氨酸激酶的VIVO成像剂
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申请号: US12022526申请日: 2008-01-30
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公开(公告)号: US20090274623A1公开(公告)日: 2009-11-05
- 发明人: Clifford L. Smith , Faisal Ahmed Syud , Brian Duh-Lan Lee , Matthew Sam Morrison , Michael Ernest Marino , Jason William Castle , Paul Schaffer , Gabriele Matschiner , Andreas Hohlbaum , Martin Huelsmeyer , Stefan Trentmann
- 申请人: Clifford L. Smith , Faisal Ahmed Syud , Brian Duh-Lan Lee , Matthew Sam Morrison , Michael Ernest Marino , Jason William Castle , Paul Schaffer , Gabriele Matschiner , Andreas Hohlbaum , Martin Huelsmeyer , Stefan Trentmann
- 申请人地址: US NY Schenectady
- 专利权人: GENERAL ELECTRIC COMPANY
- 当前专利权人: GENERAL ELECTRIC COMPANY
- 当前专利权人地址: US NY Schenectady
- 主分类号: A61K51/08
- IPC分类号: A61K51/08 ; A61K49/00 ; A61K49/14
摘要:
Provided are in vivo imaging agents comprising muteins of hTLc having detectable binding affinity for c-Met or a domain thereof, coupled to a signal generator, and the mutein coupled to a signal generator is disposed in a pharmaceutically acceptable carrier. Also provided are diagnostic methods using in vivo imaging agents comprising muteins of hTLc having detectable binding affinity for c-Met or a domain thereof.
公开/授权文献
- US1645501A Method of and apparatus for feeding fabrics 公开/授权日:1927-10-11
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