发明申请
US20090274693A1 Method of Treating Cancer using a cMet and AXL Inhibitor and an ErbB Inhibitor
审中-公开
使用cMet和AXL抑制剂和ErbB抑制剂治疗癌症的方法
- 专利标题： Method of Treating Cancer using a cMet and AXL Inhibitor and an ErbB Inhibitor
- 专利标题（中）： 使用cMet和AXL抑制剂和ErbB抑制剂治疗癌症的方法
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申请号： US12435473申请日： 2009-05-05
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公开(公告)号： US20090274693A1公开(公告)日： 2009-11-05
- 发明人: Tona M. Gilmer , James G. Greger, JR. , Li Liu , Hong Shi
- 申请人： Tona M. Gilmer , James G. Greger, JR. , Li Liu , Hong Shi
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; A61K31/47 ; A61K39/395 ; A61P35/04
摘要：
The present invention relates to a method of treating cancer in a patient comprising administering to the patient therapeutically effective amounts of:a) a compound of formula A: or a pharmaceutically acceptable salt thereof, wherein R1-R4, p, and q are as defined; and(b) an erbB inhibitor that inhibits erbB-1 or erbB-2 or erbB-3 receptor or a combination thereof. The method of the present invention addresses a need in the art with the discovery of a combination therapy that shows evidence of being a more effective therapy than previously disclosed therapies.
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