发明申请
US20090280066A1 Methods and compounds for the treatment of mucus hypersecretion
审中-公开
用于治疗粘液分泌过多的方法和化合物
- 专利标题： Methods and compounds for the treatment of mucus hypersecretion
- 专利标题（中）： 用于治疗粘液分泌过多的方法和化合物
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申请号： US11798610申请日： 2007-05-15
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公开(公告)号： US20090280066A1公开(公告)日： 2009-11-12
- 发明人: Conrad Padraig Quinn , Keith Alan Foster , John Chaddock
- 申请人： Conrad Padraig Quinn , Keith Alan Foster , John Chaddock
- 优先权： GB9818548.1 19980825
- 主分类号： A61K9/12
- IPC分类号： A61K9/12 ; C12N9/50 ; C07H21/04 ; A61K38/48 ; C12P21/06
摘要：
A method of treating mucus hypersecretion, the causative factor in chronic obstructive pulmonary disease (COPD), asthma and other clinical conditions involving COPD, comprises administering a compound that inhibits exocytosis in mucus secreting cells or neurones that control or direct mucus secretion. Also described is a compound, for use in the treatment of hypersecretion of mucus, which inhibits mucus secretion by inhibiting mucus secretion by mucus secreting cells, and/or inhibiting neurotransmitter release from neuronal cells controlling or directing mucus secretion.
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