发明申请
- 专利标题： Compounds exhibiting type X sPLA2 inhibiting effect
- 专利标题（中）： 表现出X型sPLA2抑制作用的化合物
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申请号： US12458846申请日： 2009-07-24
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公开(公告)号： US20090286796A1公开(公告)日： 2009-11-19
- 发明人: Tomoyuki Ogawa , Kaoru Seno , Kohji Hanasaki , Minoru Ikeda , Takashi Ono
- 申请人： Tomoyuki Ogawa , Kaoru Seno , Kohji Hanasaki , Minoru Ikeda , Takashi Ono
- 优先权： JP2000-195430 20000629
- 主分类号： A61K31/5025
- IPC分类号： A61K31/5025 ; C07D487/02 ; A61P43/00
摘要：
A compound represented by the general formula: wherein R20 is —CH2COOH and the like; R21 is —COCONH2 and the like; R22 is C4-C6 alkyl; and the like; R23 is —CH2—R18 wherein R18 is aryl and the like; R24 is hydrogen or C1-C6 alkyl and the like; an optical active compound, a prodrug thereof, or a pharmaceutically acceptable salt, or a solvate having type X sPLA2 inhibitory effect was found.
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