This invention provides a pneumatic tire provided with a carcass (4) comprised of one or more carcass plies formed by covering plural reinforcing cords arranged in parallel with a coating rubber and a pair of side reinforcing rubber layers (5) each having a crescent shape in section and disposed at an inside of the carcass, wherein ride comfort during usual running and durability during run-flat running are improved by applying a cord including a polyketone fiber and satisfying conditions of equation (I): σ≧−0.01×E+1.2 and equation (II): σ≧0.02 [wherein σ is a heat shrinkage stress (cN/dtex) at 177° C. and E is an elastic modulus (cN/dtex) at 25° C. under a load of 49 N] to the reinforcing cord and a rubber composition having a loss tangent (tan δ) at 25° C. and 1% strain of less than 0.12 and a viscosity (G′) at 130° C. during unvulcanization of not less than 50 MPa to the coating rubber.