发明申请
US20090298054A1 Epigenetic methods and nucleic acids for the detection of breast cell proliferative disorders
审中-公开
用于检测乳腺增生性疾病的表观遗传学方法和核酸
- 专利标题: Epigenetic methods and nucleic acids for the detection of breast cell proliferative disorders
- 专利标题(中): 用于检测乳腺增生性疾病的表观遗传学方法和核酸
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申请号: US11632824申请日: 2005-07-18
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公开(公告)号: US20090298054A1公开(公告)日: 2009-12-03
- 发明人: Ralf Lesche , Anne Fassbender , Klaus Juenemann , John Foekens , John W. Martens
- 申请人: Ralf Lesche , Anne Fassbender , Klaus Juenemann , John Foekens , John W. Martens
- 申请人地址: DE Berlin
- 专利权人: Epigenomics AG
- 当前专利权人: Epigenomics AG
- 当前专利权人地址: DE Berlin
- 优先权: EP04016926.0 20040718
- 国际申请: PCT/EP05/07830 WO 20050718
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; C07H21/04
摘要:
The present application provides methods and nucleic acids for the detection and differentiation of breast cell proliferative disorders. This is achieved by the analysis of the methylation of a panel of genes, or subsets thereof. The invention may be used for the detection and/or differentiation of a variety of tissue types including breast cancer and benign breast disorders as well as other cancers and tissue types.
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