发明申请
- 专利标题： HIV-1 LATENCY MODEL FOR HIGH THROUGHPUT SCREENING
- 专利标题（中）： 用于高通量筛选的HIV-1 LATENCY模型
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申请号： US12096245申请日： 2006-11-27
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公开(公告)号： US20090305227A1公开(公告)日： 2009-12-10
- 发明人: Joseph P. Dougherty , Sofiya Micheva-Viteva , Stuart W. Peltz , Yacov Ron , Annmarie L. Pacchia
- 申请人： Joseph P. Dougherty , Sofiya Micheva-Viteva , Stuart W. Peltz , Yacov Ron , Annmarie L. Pacchia
- 申请人地址： US NJ New Brunswick
- 专利权人： UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY
- 当前专利权人： UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY
- 当前专利权人地址： US NJ New Brunswick
- 国际申请： PCT/US06/45483 WO 20061127
- 主分类号： C12Q1/70
- IPC分类号： C12Q1/70 ; C12N5/06
摘要：
Isolated, latently infected T cell lines are provided that can be utilized in high throughput screening to discover compounds capable of activating HIV-I. The T cell lines harbor a latent HIV-I derived vector pro virus, which upon activation expresses a marker for late viral gene expression due to the insertion of the marker gene in the position of HIV-I envelope.
公开/授权文献
- US08247167B2 HIV-1 latency model for high throughput screening 公开/授权日：2012-08-21