A space domain filter detecting method in a multi-antennas wireless communication system, processing differently with the interference from the time domain and the space domain, which proceeds the interference elimination in matched filter manner for the interference signals from all antennas in the other time, and proceeds the filtering in corresponding manner for the interference signals from the other antennas in present time, comprises the following steps: firstly, the received signals are matched-combined in time domain and space domain; secondly, with the combined signals as the observation value for detecting, the filtering is proceeded in space domain in corresponding manner; thirdly, the estimated value is subtracted from the filtered signals, and the result is taken as the detecting result to output, and then is sent to the determiner in non-error control coding system to get the symbol hard determination output or is sent to the determiner in error control coding system to get the symbol soft determination output that finally sent to the coder. The method promotes the transmission rate and the anti-interference ability and advances the spectrum efficiency.