发明申请
- 专利标题： LASER DESORPTION IONIZATION AND PEPTIDE SEQUENCING ON LASER INDUCED SILICON MICROCOLUMN ARRAYS
- 专利标题（中）： 在激光诱导硅微阵列上的激光解吸离子和肽序列
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申请号： US11674671申请日： 2007-02-14
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公开(公告)号： US20090321626A1公开(公告)日： 2009-12-31
- 发明人: Akos Vertes , Yong Chen
- 申请人： Akos Vertes , Yong Chen
- 主分类号： H01J49/26
- IPC分类号： H01J49/26 ; B32B3/10 ; B29C59/16
摘要：
The present invention provides a method of producing a laser-patterned silicon surface, especially silicon wafers for use in laser desorption ionization (LDI-MS) (including MALDI-MS and SELDI-MS), devices containing the same, and methods of testing samples employing the same. The surface is prepared by subjecting a silicon substrate to multiple laser shots from a high-power picosecond or femtosecond laser while in a processing environment, e.g., underwater, and generates a remarkable homogenous microcolumn array capable of providing an improved substrate for LDI-MS.
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