发明申请
- 专利标题： Two-component genome flavivirus and uses thereof
- 专利标题（中）： 双组分基因组黄病毒及其用途
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申请号： US12151491申请日： 2008-05-07
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公开(公告)号： US20090324623A1公开(公告)日： 2009-12-31
- 发明人: Ilya V. Frolov , Alexandr V. Shustov
- 申请人： Ilya V. Frolov , Alexandr V. Shustov
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; C07H21/04 ; C12N5/08 ; C12P19/34 ; A61P31/00
摘要：
The present invention discloses a two-component genome flavivirus and a method for propagating such virus. Since the genetic material of this flavivirus is distributed between two genomes, the flavivirus is deficient in replication, incapable of causing disease but capable of inducing an immune response. Nevertheless, the design of the replication deficient flavivirus discussed herein allows propagation of these flaviviruses at industrial level.
公开/授权文献
- US08394620B2 Two-component genome flavivirus and uses thereof 公开/授权日：2013-03-12
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