Invention Application
US20090325939A1 1H-INDAZOLES, BENZOTHIAZOLES, 1,2-BENZOISOXAZOLES, 1,2-BENZOISOTHIAZOLES, AND CHROMONES AND PREPARATION AND USES THEREOF
审中-公开
1H-INDAZOLES，BENZOTHIAZOLES，1,2-BENZOISOXAZOLES，1,2-BENZOISOTHIAZOLES AND AND CHROMONES AND Preparation and Preparation and
- Patent Title: 1H-INDAZOLES, BENZOTHIAZOLES, 1,2-BENZOISOXAZOLES, 1,2-BENZOISOTHIAZOLES, AND CHROMONES AND PREPARATION AND USES THEREOF
- Patent Title (中): 1H-INDAZOLES，BENZOTHIAZOLES，1,2-BENZOISOXAZOLES，1,2-BENZOISOTHIAZOLES AND AND CHROMONES AND Preparation and Preparation and
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Application No.: US12553538Application Date: 2009-09-03
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Publication No.: US20090325939A1Publication Date: 2009-12-31
- Inventor: Wenge XIE , Brian Herbert , Richard A. Schumacher , Jianguo Ma , True Minh Nguyen , Carla Maria Gauss , Ashok Tehim
- Applicant: Wenge XIE , Brian Herbert , Richard A. Schumacher , Jianguo Ma , True Minh Nguyen , Carla Maria Gauss , Ashok Tehim
- Main IPC: A61K31/551
- IPC: A61K31/551 ; C07D243/10 ; A61P25/00
Abstract:
The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nAChR), activation of nAChRs, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds (indazoles and benzothiazoles), which act as ligands for the α7 nAChR subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.
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