发明申请
US20090325939A1 1H-INDAZOLES, BENZOTHIAZOLES, 1,2-BENZOISOXAZOLES, 1,2-BENZOISOTHIAZOLES, AND CHROMONES AND PREPARATION AND USES THEREOF
审中-公开
1H-INDAZOLES，BENZOTHIAZOLES，1,2-BENZOISOXAZOLES，1,2-BENZOISOTHIAZOLES AND AND CHROMONES AND Preparation and Preparation and
- 专利标题： 1H-INDAZOLES, BENZOTHIAZOLES, 1,2-BENZOISOXAZOLES, 1,2-BENZOISOTHIAZOLES, AND CHROMONES AND PREPARATION AND USES THEREOF
- 专利标题（中）： 1H-INDAZOLES，BENZOTHIAZOLES，1,2-BENZOISOXAZOLES，1,2-BENZOISOTHIAZOLES AND AND CHROMONES AND Preparation and Preparation and
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申请号： US12553538申请日： 2009-09-03
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公开(公告)号： US20090325939A1公开(公告)日： 2009-12-31
- 发明人: Wenge XIE , Brian Herbert , Richard A. Schumacher , Jianguo Ma , True Minh Nguyen , Carla Maria Gauss , Ashok Tehim
- 申请人： Wenge XIE , Brian Herbert , Richard A. Schumacher , Jianguo Ma , True Minh Nguyen , Carla Maria Gauss , Ashok Tehim
- 主分类号： A61K31/551
- IPC分类号： A61K31/551 ; C07D243/10 ; A61P25/00
摘要：
The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nAChR), activation of nAChRs, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds (indazoles and benzothiazoles), which act as ligands for the α7 nAChR subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.