发明申请
US20090326006A1 Benzazole Derivatives, Compositions, and Methods of Use as Beta-Secretase Inhibitors
有权
苯并唑衍生物，组合物和使用方法作为β-分泌酶抑制剂
- 专利标题： Benzazole Derivatives, Compositions, and Methods of Use as Beta-Secretase Inhibitors
- 专利标题（中）： 苯并唑衍生物，组合物和使用方法作为β-分泌酶抑制剂
-
申请号： US11885096申请日： 2006-03-14
-
公开(公告)号： US20090326006A1公开(公告)日： 2009-12-31
- 发明人: Adnan M.M. Mjalli , David Jones , Devi Reddy Gohmmukkula , Guoxiang Huang , Jeff Zhu , Mohan Rao , Robert C. Andrews , Tan Ren
- 申请人： Adnan M.M. Mjalli , David Jones , Devi Reddy Gohmmukkula , Guoxiang Huang , Jeff Zhu , Mohan Rao , Robert C. Andrews , Tan Ren
- 国际申请： PCT/US06/09049 WO 20060314
- 主分类号： A61K31/4725
- IPC分类号： A61K31/4725 ; C07D401/14 ; A61P25/28
摘要：
The present invention is directed to benzazole compounds that inhibit β-site amyloid precursor protein-cleaving enzyme (BACE) and that may be useful in the treatment or prevention of diseases in which BACE is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which BACE is involved.
公开/授权文献
信息查询
IPC分类:
