发明申请
US20100009991A1 POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS
失效
多环酸化合物作为CRTH2拮抗剂和抗癌药物有用
- 专利标题: POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS
- 专利标题(中): 多环酸化合物作为CRTH2拮抗剂和抗癌药物有用
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申请号: US12518280申请日: 2007-12-13
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公开(公告)号: US20100009991A1公开(公告)日: 2010-01-14
- 发明人: Tadashi Terasaka , Tatsuya Zenkoh , Hisashi Hayashida , Hiroshi Matsuda , Junji Sato , Yoshimasa Imamura , Hiroshi Nagata , Norio Seki , Yoshiyuki Tenda , Mamoru Tasaki , Masahiro Takeda , Seiichiro Tabuchi , Minoru Yasuda , Kazunori Tsubaki
- 申请人: Tadashi Terasaka , Tatsuya Zenkoh , Hisashi Hayashida , Hiroshi Matsuda , Junji Sato , Yoshimasa Imamura , Hiroshi Nagata , Norio Seki , Yoshiyuki Tenda , Mamoru Tasaki , Masahiro Takeda , Seiichiro Tabuchi , Minoru Yasuda , Kazunori Tsubaki
- 申请人地址: JP Chuo-ku ,Tokyo
- 专利权人: Astellas Pharma Inc.
- 当前专利权人: Astellas Pharma Inc.
- 当前专利权人地址: JP Chuo-ku ,Tokyo
- 国际申请: PCT/JP2007/074475 WO 20071213
- 主分类号: A61K31/50
- IPC分类号: A61K31/50 ; C07D237/02 ; C07D211/72 ; C07C65/00 ; C07C69/76 ; C07D263/30 ; A61K31/44 ; A61K31/421 ; A61K31/215 ; A61K31/19 ; A61P37/08
摘要:
The present invention relates to a novel compound or a salt thereof, which is useful as a CRTH2 antagonist, especially as a medicament for disorder that participates eosinophil, for example, allergic disorder such as asthma, allergic rhinitis, allergic dermatitis, conjunctival inflammation, hives, eosinophilic bronchitis, food allergy, inflammation of the nasal sinuses, multiple sclerosis, angiitis, or chronic obstructive pulmonary disease (COPD) and the like.