发明申请
- 专利标题: Camptothecin-Binding Moiety Conjugates
- 专利标题(中): 喜树碱结合部位缀合物
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申请号: US12538922申请日: 2009-08-11
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公开(公告)号: US20100015046A1公开(公告)日: 2010-01-21
- 发明人: Serengulam V. Govindan , David M. Goldenberg , Sung-Ju Moon
- 申请人: Serengulam V. Govindan , David M. Goldenberg , Sung-Ju Moon
- 申请人地址: US NJ Morris Plains
- 专利权人: IMMUNOMEDICS, INC.
- 当前专利权人: IMMUNOMEDICS, INC.
- 当前专利权人地址: US NJ Morris Plains
- 主分类号: A61K31/4375
- IPC分类号: A61K31/4375 ; A61K51/00 ; A61K31/7088 ; A61K39/395 ; A61K38/02 ; A61P31/00 ; A61P35/00
摘要:
The invention relates to therapeutic conjugates with improved ability to target various diseased cells containing a targeting moiety (such as an antibody or antibody fragment), a linker and a camptothecin as a therapeutic moiety, and further relates to processes for making and using the said conjugates.
公开/授权文献
- US08268317B2 Camptothecin-binding moiety conjugates 公开/授权日:2012-09-18
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