发明申请
- 专利标题： Inhibitor Compounds and Cancer Treatment Methods
- 专利标题（中）： 抑制剂化合物和癌症治疗方法
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申请号： US12505295申请日： 2009-07-17
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公开(公告)号： US20100015140A1公开(公告)日： 2010-01-21
- 发明人: Wayne R. Danter
- 申请人： Wayne R. Danter
- 申请人地址： CA London
- 专利权人： CRITICAL OUTCOME TECHNOLOGIES INC.
- 当前专利权人： CRITICAL OUTCOME TECHNOLOGIES INC.
- 当前专利权人地址： CA London
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; A61K31/497
摘要：
A synergistically effective combination of an anti-cancer agent and a therapeutic compound, such as an mTOR-Rictor complex inhibitor, a Serine 473 phosphorylation inhibitor, an AKT2 inhibitor, or a combination thereof, for use in the treatment of cancer, and methods and uses thereof. Also included are methods and uses of a thiosemicarbazone for treating a cancer in a mammal in need thereof characterized by over-expression of RAS, by an EGFR mutation, and/or by over-expression of AKT2.
公开/授权文献
- US08138191B2 Inhibitor compounds and cancer treatment methods 公开/授权日：2012-03-20
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