发明申请
US20100016379A1 Terephthalamate Compounds and Compositions, and Their Use as HIV Integrase Inhibitors
审中-公开
对苯二甲酸酯化合物和组合物及其作为HIV整合酶抑制剂的用途
- 专利标题： Terephthalamate Compounds and Compositions, and Their Use as HIV Integrase Inhibitors
- 专利标题（中）： 对苯二甲酸酯化合物和组合物及其作为HIV整合酶抑制剂的用途
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申请号： US12300171申请日： 2007-04-18
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公开(公告)号： US20100016379A1公开(公告)日： 2010-01-21
- 发明人: Yun He , Zhiwei Wang , Baogen Wu
- 申请人： Yun He , Zhiwei Wang , Baogen Wu
- 申请人地址： BM BM Hamilton
- 专利权人： IRM LLC
- 当前专利权人： IRM LLC
- 当前专利权人地址： BM BM Hamilton
- 国际申请： PCT/US07/09540 WO 20070418
- 主分类号： A61K31/195
- IPC分类号： A61K31/195 ; C07C229/38 ; C07D213/56 ; A61K31/44
摘要：
Described herein are compounds having a terephthalamate structural feature. Also described herein, are methods of making such compounds, methods of using such compounds to modulate the activity of HIV integase, and pharmaceutical compositions and medicaments comprising such compounds. Also described herein are methods of using such compounds, pharmaceutical compositions and medicaments to treat and/or prevent and/or inhibit and/or ameliorate the pathology and/or symptomology of AIDS or infection with HIV.
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