发明申请
US20100016399A1 GLYT1 Transporter Inhibitors and Uses Thereof in Treatment of Neurological and Neuropsychiatric Disorders
审中-公开
GLYT1转运蛋白抑制剂及其在神经和神经精神障碍治疗中的应用
- 专利标题： GLYT1 Transporter Inhibitors and Uses Thereof in Treatment of Neurological and Neuropsychiatric Disorders
- 专利标题（中）： GLYT1转运蛋白抑制剂及其在神经和神经精神障碍治疗中的应用
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申请号： US12524582申请日： 2008-01-30
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公开(公告)号： US20100016399A1公开(公告)日： 2010-01-21
- 发明人: Nadia Mamoona Ahmad , Albert Andrzej Jaxa-Chamiec , Justine Yeun Quai Lai , Roderich Alan Porter
- 申请人： Nadia Mamoona Ahmad , Albert Andrzej Jaxa-Chamiec , Justine Yeun Quai Lai , Roderich Alan Porter
- 优先权： GB0701985.4 20070201
- 国际申请： PCT/EP2008/051078 WO 20080130
- 主分类号： A61K31/40
- IPC分类号： A61K31/40 ; C07D209/54 ; A61P25/18
摘要：
Compounds of formula (I) or a salt thereof are provided: wherein R1, R2, R3, R4, R5, R6, R7, R8, R21 and m are as defined in the description. Uses of the compounds as medicaments, and in the manufacture of medicament for treating neurological and neuropsychiatric disorders, in particular psychoses, dementia or attention deficit disorder are also disclosed. The invention further discloses pharmaceutical compositions and combinations comprising the compounds.
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