发明申请
- 专利标题： 3,4,(5)-SUBSTITUTED TETRAHYDROPHYRIDINES
- 专利标题（中）： 3,4，（5） - 衍生的四氢吡啶类
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申请号： US11722398申请日： 2006-01-12
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公开(公告)号： US20100029647A1公开(公告)日： 2010-02-04
- 发明人: Keiichi Masuya , Osamu Irie , Atsuko Nihonyanagi , Atsushi Toyao , Takanori Kanazawa
- 申请人： Keiichi Masuya , Osamu Irie , Atsuko Nihonyanagi , Atsushi Toyao , Takanori Kanazawa
- 优先权： GB0500784.4 20050114
- 国际申请： PCT/EP06/00216 WO 20060112
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; C07D401/12 ; C07D213/56 ; C07D413/12 ; A61K31/4439 ; A61K31/4406
摘要：
3,4(,5)-substituted tetrahydropyridine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,4(,5)-substituted tetrahydropyridine compound, and/or a method of treatment comprising administering a 3,4(,5)-substituted tetrahydropyridine compound, a method for the manufacture of a 3,4(,5)-substituted tetrahydropyridine compound, and novel intermediates and partial steps for its synthesis.The 3,4(,5)-substituted tetrahydropyridine compounds have the formula I wherein the substituents and symbols are as described in the specification.