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发明申请
US20100034748A1 Molecular imaging probes based on loaded reactive nano-scale latex 审中-公开
基于负载的反应性纳米级胶乳的分子成像探针

Molecular imaging probes based on loaded reactive nano-scale latex
摘要：
The present invention relates to a loaded reactive nanoscale latex particle synthesized from mixture of monomers containing water insoluble monomers, at least two ethylenically functionalities monomers, halo-aromatic-polyethyleneglycol-methacrylate, polyethyleneglycolacrylate containing macromonomers, and up to 10 wt % other ethylenic monomers different from above monomers. The reactive halo-aromatic groups on the surface of latex particle are servable as linkers to react with peptides, antibodies, nucleic acids, ligands or other biomolecules.
摘要（中）：

本发明涉及由含有水不溶性单体，至少两种烯键式官能团单体，卤代芳族聚乙二醇 - 甲基丙烯酸酯，含聚乙二醇丙烯酸酯的大分子单体和至多10重量％的其它乙烯单体的混合物的混合物合成的负载的反应性纳米尺寸胶乳颗粒 从上述单体。 胶乳颗粒表面上的反应性卤代芳族基团可作为接头与肽，抗体，核酸，配体或其他生物分子反应。

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