发明申请
- 专利标题： ANTISENSE MODULATION OF CONNECTIVE TISSUE GROWTH FACTOR EXPRESSION
- 专利标题（中）： 连接组织生长因子表达的抗原调节
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申请号： US12011761申请日： 2008-01-28
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公开(公告)号： US20100035964A1公开(公告)日： 2010-02-11
- 发明人: William Gaarde , Andrew T. Watt , Brett P. Monia , Mausumee Guha
- 申请人： William Gaarde , Andrew T. Watt , Brett P. Monia , Mausumee Guha
- 专利权人： Isis Pharmaceuticals, Inc.
- 当前专利权人： Isis Pharmaceuticals, Inc.
- 主分类号： A61K31/7088
- IPC分类号： A61K31/7088 ; C07H21/04
摘要：
Antisense compounds, compositions and methods are provided for modulating the expression of connective tissue growth factor. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding connective tissue growth factor. Methods of using these compounds for modulation of connective tissue growth factor expression and for treatment of diseases associated with expression of connective tissue growth factor are provided.
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