发明申请
US20100035973A1 DISRUPTION OF PROGRAMMED DEATH 1 (PD-1) LIGAND TO ADJUVANT ADENO-ASSOCIATED VIRUS VECTOR VACCINES
审中-公开
编程死亡1号(PD-1)配偶对ADJOANT ADENO相关病毒载体疫苗的破坏
- 专利标题: DISRUPTION OF PROGRAMMED DEATH 1 (PD-1) LIGAND TO ADJUVANT ADENO-ASSOCIATED VIRUS VECTOR VACCINES
- 专利标题(中): 编程死亡1号(PD-1)配偶对ADJOANT ADENO相关病毒载体疫苗的破坏
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申请号: US12373880申请日: 2007-07-13
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公开(公告)号: US20100035973A1公开(公告)日: 2010-02-11
- 发明人: Christopher Walker
- 申请人: Christopher Walker
- 申请人地址: US OH Columbus
- 专利权人: Nationwide Children's Hospital, Inc.
- 当前专利权人: Nationwide Children's Hospital, Inc.
- 当前专利权人地址: US OH Columbus
- 国际申请: PCT/US2007/073474 WO 20070713
- 主分类号: A61K48/00
- IPC分类号: A61K48/00 ; C12N15/861 ; C12N5/10
摘要:
The invention provides for methods of modulating an immune response against a therapeutic polypeptide or an antigenic polypeptide delivered via rAAV comprising administering a modulator of programmed death-1 (PD-1) signaling.
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