发明申请
- 专利标题： PURIFIED RECOMBINANT BATROXOBIN WITH HIGH SPECIFIC ACTIVITY
- 专利标题（中）： 具有高特异性活性的纯化重组蛋白
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申请号： US12568234申请日： 2009-09-28
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公开(公告)号： US20100047229A1公开(公告)日： 2010-02-25
- 发明人: Xiudong Huang , Peixin Chen , Xuegong Pan , Qiang Wang
- 申请人： Xiudong Huang , Peixin Chen , Xuegong Pan , Qiang Wang
- 申请人地址： CN Shanghai CN Shanghai
- 专利权人： Zhifang Cao,SHANGHAI WANXING BIOPHARMACEUTICALS, CO., LTD.
- 当前专利权人： Zhifang Cao,SHANGHAI WANXING BIOPHARMACEUTICALS, CO., LTD.
- 当前专利权人地址： CN Shanghai CN Shanghai
- 主分类号： A61K38/48
- IPC分类号： A61K38/48 ; C12N9/50
摘要：
A purified recombinant batroxobin with high specific activity, which has the following properties: (a) the batroxobin has a molecular weight of 29-32 kDa; (b) at least 90% of the batroxobin have 6 pairs of disulfide bonds which correctly match at Cys7-Cys139, Cys26-Cys42, Cys74-Cys230, Cys118-Cys184, Cys150-Cys163 and Cysl174-Cys199; (c) positions 146 and 225 in SEQ ID NO:1 are modified as N-glycosylation; and (d) the specific activity of the batroxobin is equal to or greater than 1500 KU/mg protein.
公开/授权文献
- US07939067B2 Purified recombinant batroxobin with high specific activity 公开/授权日：2011-05-10
信息查询
IPC分类:
