发明申请
US20100048576A1 PYRIDOPYRAZINES AND DERIVATIVES THEREOF AS ALK AND c-MET INHIBITORS
有权
吡嗪和衍生物作为ALK和c-MET抑制剂
- 专利标题: PYRIDOPYRAZINES AND DERIVATIVES THEREOF AS ALK AND c-MET INHIBITORS
- 专利标题(中): 吡嗪和衍生物作为ALK和c-MET抑制剂
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申请号: US12566362申请日: 2009-09-24
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公开(公告)号: US20100048576A1公开(公告)日: 2010-02-25
- 发明人: Bruce D. Dorsey , Karen L. Milkiewicz , Douglas A. Pippin , Jay P. Theroff , Ted Underiner , Linda Weinberg , Craig A. Zificsak
- 申请人: Bruce D. Dorsey , Karen L. Milkiewicz , Douglas A. Pippin , Jay P. Theroff , Ted Underiner , Linda Weinberg , Craig A. Zificsak
- 申请人地址: US PA Frazer
- 专利权人: CEPHALON, INC.
- 当前专利权人: CEPHALON, INC.
- 当前专利权人地址: US PA Frazer
- 主分类号: A61K31/4985
- IPC分类号: A61K31/4985 ; C07D471/04 ; C07D401/14 ; C07D403/14
摘要:
The present invention provides a compound of Formula I or a pharmaceutically acceptable salt form thereof, wherein A, L1, R1, R2, R3, R4, R5, R6, and X are as defined herein. The compounds of Formula I have ALK and/or c-Met inhibitory activity, and may be used to treat ALK- or c-Met-mediated disorders or conditions.
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