发明申请
US20100048656A1 GLYT1 TRANSPORTER INHIBITORS AND USES THEREOF IN TREATMENT OF NEUROLOGICAL AND NEUROPSYCHIATRIC DISORDERS
审中-公开
GLYT1运输商抑制剂及其在治疗神经病学和神经病学疾病中的应用
- 专利标题： GLYT1 TRANSPORTER INHIBITORS AND USES THEREOF IN TREATMENT OF NEUROLOGICAL AND NEUROPSYCHIATRIC DISORDERS
- 专利标题（中）： GLYT1运输商抑制剂及其在治疗神经病学和神经病学疾病中的应用
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申请号： US12524578申请日： 2008-01-30
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公开(公告)号： US20100048656A1公开(公告)日： 2010-02-25
- 发明人: Nadia Mamoona Ahmad , Daniele Andreotti , Albert Andrzej Jaxa-Chamiec , Justine Yeun Quai Lai
- 申请人： Nadia Mamoona Ahmad , Daniele Andreotti , Albert Andrzej Jaxa-Chamiec , Justine Yeun Quai Lai
- 优先权： GB0701959.9 20070201; GB0701982.1 20070201
- 国际申请： PCT/EP08/51079 WO 20080130
- 主分类号： A61K31/4164
- IPC分类号： A61K31/4164 ; C07D235/02 ; A61P25/18
摘要：
Compounds of formula (I) or a salt thereof are provided: wherein R6, R7, R8, R9, X, Ar, n, and m are as defined in the description. Uses of the compounds as medicaments, and in the manufacture of medicament for treating neurological and neuropsychiatric disorders, in particular psychoses, dementia or attention deficit disorder are also disclosed. The invention further discloses pharmaceutical compositions and combinations comprising the compounds.
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