An in-vivo sensing system including an in-vivo sensing device, a data recorder a receiver and a work station. The data recorder receives data signal from the in-vivo sensing device during an acquisition period. Batches of the data signal may be transmitted from the data recorder to a receiver, as soon as a batch has been received by the data recorder. The batches of data signal received by the receiver may be downloaded to the workstation as soon as each batch is received by the receiver. Signals are typically transmitted from the data recorder to the receiver through wireless transmission techniques such as cellular transmission, WLAN (Wireless Local Area Network) transmission, BT (BlueTooth) transmission and Wimax (Worldwide interoperability for Microwave Access) transmission.