发明申请
- 专利标题: PEPTIDES SEQUENCES AND COMPOSITIONS
- 专利标题(中): 肽序列和组合物
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申请号: US12282132申请日: 2007-03-09
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公开(公告)号: US20100055119A1公开(公告)日: 2010-03-04
- 发明人: Gregory Alan Stoloff , Wlison Romero Caparros-Wanderley
- 申请人: Gregory Alan Stoloff , Wlison Romero Caparros-Wanderley
- 专利权人: Pep Tcell Limited
- 当前专利权人: Pep Tcell Limited
- 优先权: GB0604920.9 20060310; GB0614260.8 20060718
- 国际申请: PCT/GB07/00812 WO 20070309
- 主分类号: A61K39/00
- IPC分类号: A61K39/00 ; C07K7/06 ; C07K7/08 ; C07K14/00
摘要:
Provided is a polypeptide having no more than 100 amino acids, which polypeptide comprises one or more sequences having at least 60% homology with any of SEQ ID 1-4, or comprises two or more epitopes having 7 amino acids or more, each epitope having at least 60% homology with a sub-sequence of any of SEQ ID 1-4 that has the same length as the epitope: SEQ ID 1 GDTWAGVEAIIRILQQLLFIHFRIGCQHSR SEQ ID 2 KVGSLQYLALTALITPKKIKPPLPSVKKLTEDRWNKPQKT SEQ ID 3 EPVPLQLPPLERLTLDCSEDCGTSGTQ SEQ ID 4 YKGALDLSHFLKEKGGLEGLIYSQKRQDILDLWVYHTQGYFPD wherein, the polypeptide is immunogenic in a vertebrate expressing a major histocompatibility complex (MHC) allele, and wherein the polypeptide is not a complete HIV virus protein.
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