发明申请
- 专利标题： Method for the Quantitative Analysis of the Number of Copies of a Pre-Determined Sequence in a Cell
- 专利标题（中）： 定量分析细胞中预先确定序列的拷贝数的方法
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申请号： US11992428申请日： 2006-08-07
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公开(公告)号： US20100055679A1公开(公告)日： 2010-03-04
- 发明人: Christoph Gauer , Wolfgang Mann
- 申请人： Christoph Gauer , Wolfgang Mann
- 优先权： DE102005045560.3 20050923
- 国际申请： PCT/EP2006/007805 WO 20060807
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68
摘要：
The invention relates to a method for the quantitative analysis of the number of a pre-determined sequence, and optionally of sequences homologous to the pre-determined sequence, in a biological sample, whereby a defined quantity of a biological sample is subjected to at least one amplification reaction which is adapted in such a way as to amplify at least two non-homologous sequences contained in the pre-determined sequence. The number of different amplification products obtained is then determined and compared with a frequency distribution. The invention further relates to a kit for the quantitative analysis of the number of a pre-determined sequence in a biological sample, and a device which is especially suitable for carrying out the inventive method.
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