发明申请
US20100056646A1 Hydroswellable, segmented, aliphatic polyurethane ureas and intra-articular devices therefrom
审中-公开
可湿性,分段,脂肪族聚氨酯脲和其中的关节内装置
- 专利标题: Hydroswellable, segmented, aliphatic polyurethane ureas and intra-articular devices therefrom
- 专利标题(中): 可湿性,分段,脂肪族聚氨酯脲和其中的关节内装置
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申请号: US12586788申请日: 2009-09-28
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公开(公告)号: US20100056646A1公开(公告)日: 2010-03-04
- 发明人: Shalaby W. Shalaby , Georgios T. Hilas
- 申请人: Shalaby W. Shalaby , Georgios T. Hilas
- 主分类号: A61K47/30
- IPC分类号: A61K47/30 ; C08G18/00 ; C08G18/48 ; C08G77/04 ; B05D3/00
摘要:
Hydroswellable, non-absorbable, biostable, segmented, aliphatic polyether-urethane-ureas or polyether-siloxane-urethane-ureas form a single component, intra-articular device for restoring joints with artificial cartilage, as a cartilage substitute for degenerated cartilage and/or for enhancing the remaining cartilage of an arthritic joint. The intra-articular devices can be bicomponent in nature comprising a biostable, articulating, non-absorbable component and an absorbable component in the form of a solid or microporous liner interfacing with the tissue of defective or diseased joint to support in situ tissue engineering. One or more bioactive agent with specific pharmacological function can be incorporated in the single or bicomponent intra-articular devices to supplement their structural functions.
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