发明申请
US20100061983A1 Method of inhibiting leukocytes with human cxc chemokine receptor 3 antibody
审中-公开
用人cxc趋化因子受体3抗体抑制白细胞的方法
- 专利标题： Method of inhibiting leukocytes with human cxc chemokine receptor 3 antibody
- 专利标题（中）： 用人cxc趋化因子受体3抗体抑制白细胞的方法
-
申请号： US11903330申请日： 2007-09-21
-
公开(公告)号： US20100061983A1公开(公告)日： 2010-03-11
- 发明人: Marcel Loetscher , Bernhard Moser , Shixin Qin , Charles R. Mackay
- 申请人： Marcel Loetscher , Bernhard Moser , Shixin Qin , Charles R. Mackay
- 申请人地址： US MA Cambridge CH Bern
- 专利权人： Millennium Pharmaceuticals, Inc.,Theodor-Kocher Institute
- 当前专利权人： Millennium Pharmaceuticals, Inc.,Theodor-Kocher Institute
- 当前专利权人地址： US MA Cambridge CH Bern
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07H21/02 ; G01N33/53
摘要：
The present invention relates to proteins or polypeptides, referred to herein as isolated and/Or recombinant mammalian (e.g., human) IP-10/Mig receptor proteins designated CXC Chemokine Receptor 3 (CXCR3) and variants thereof, including those characterized by selective binding of one or more chemokines (e.g., IP-10 and/or Mig), and/or the ability to induce a cellular response (e.g., chemotaxis, exocytosis). Antibodies reactive with CXCR3 receptors can be produced using the proteins or variants thereof or host cells comprising same as immunogen.
信息查询
