发明申请
US20100062011A1 Peptide Vaccine for Inducing the Production of Anti-Amyloid ß-Peptide Antibody
失效
用于诱导抗淀粉样蛋白β肽抗体生产的肽疫苗
- 专利标题： Peptide Vaccine for Inducing the Production of Anti-Amyloid ß-Peptide Antibody
- 专利标题（中）： 用于诱导抗淀粉样蛋白β肽抗体生产的肽疫苗
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申请号： US12280535申请日： 2007-02-16
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公开(公告)号： US20100062011A1公开(公告)日： 2010-03-11
- 发明人: Akira Yano
- 申请人： Akira Yano
- 申请人地址： JP Okayama
- 专利权人： Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
- 当前专利权人： Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
- 当前专利权人地址： JP Okayama
- 优先权： JP2006-044808 20060222
- 国际申请： PCT/JP2007/052828 WO 20070216
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; C07K14/00 ; C07H21/04 ; A61P25/28
摘要：
An object of the present invention is to provide a peptide vaccine for preventing and/or treating diseases caused by amyloid β-peptide, such as Alzheimer's disease. The present invention solves the above object by providing a peptide vaccine constructed by inserting a peptide having an amino acid sequence of a cell attachment motif of a cell adhesive molecule to a peptide which consists of a peptide having an amino acid sequence of multiagretope type T-cell epitope, which has been generated immunological memory, or a peptide including the same; an linker peptide; and a peptide having an amino acid sequence of a B cell epitope which is a specific region of amyloid β-peptide or a peptide including the same.
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