发明申请
US20100069417A1 NOVEL PHENYL(4-PHENYLPYRIMIDIN-2-YL)AMINE DERIVATIVES, THEIR PREPARATION, AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND IN PARTICULAR AS IKK INHIBITORS
审中-公开
新型苯基(4-苯基嘧啶-2-基)胺衍生物,其制备,作为药物,药物组合物,特别是IKK抑制剂
- 专利标题: NOVEL PHENYL(4-PHENYLPYRIMIDIN-2-YL)AMINE DERIVATIVES, THEIR PREPARATION, AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND IN PARTICULAR AS IKK INHIBITORS
- 专利标题(中): 新型苯基(4-苯基嘧啶-2-基)胺衍生物,其制备,作为药物,药物组合物,特别是IKK抑制剂
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申请号: US12496105申请日: 2009-07-01
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公开(公告)号: US20100069417A1公开(公告)日: 2010-03-18
- 发明人: Monsif BOUABOULA , Pierre CASELLAS , Sherri DUDAL , Regine FLOUTARD , Maria MENDEZ-PEREZ , Jean-Flaubert NGUEFACK , Jacob-Alsboek OLSEN , Bernard TONNERRE , Jean WAGNON
- 申请人: Monsif BOUABOULA , Pierre CASELLAS , Sherri DUDAL , Regine FLOUTARD , Maria MENDEZ-PEREZ , Jean-Flaubert NGUEFACK , Jacob-Alsboek OLSEN , Bernard TONNERRE , Jean WAGNON
- 申请人地址: FR Paris
- 专利权人: SANOFI-AVENTIS
- 当前专利权人: SANOFI-AVENTIS
- 当前专利权人地址: FR Paris
- 优先权: FR0700065 20070105
- 主分类号: A61K31/506
- IPC分类号: A61K31/506 ; C07D401/12 ; C07D401/14 ; C07D409/14 ; C07D417/14 ; A61P29/00 ; A61P3/10 ; A61P35/00
摘要:
The disclosure relates to a compound of formula (I): wherein R, R2, R3, R4, R5, Z, W and D are as defined in the specification, to compositions containing them, to processes for preparing them, and to their use in the treatment or prevention of conditions capable of being modulated by the inhibition of the activity of protein kinases.
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