A refrigerant system utilizes an expander that provides a more efficient expansion process and recovers at least a portion of energy from this expansion process. At least a portion of refrigerant that has been at least partially expanded in the expander is tapped and passed through an economizer heat exchanger. In the economizer heat exchanger, the tapped refrigerant cools a main circuit refrigerant increasing its thermodynamic potential. Further, a compression section is provided with at least two compressors operating in tandem and allowing for multiple stages of unloading. By selectively utilizing one or more of the tandem compressors, the economizer cycle, and the expander, the refrigerant system can achieve very efficient operation and provide enhanced control flexibility, in particular, for the CO2 refrigerant system operating in the transcritical cycle.