发明申请
US20100075351A1 BIOLUMINESCENT DETECTION OF CYANOHYDROXY BENZOTHIAZOLE COMPOUNDS
有权
氰化羟基苯并噻唑化合物的生物发光检测
- 专利标题: BIOLUMINESCENT DETECTION OF CYANOHYDROXY BENZOTHIAZOLE COMPOUNDS
- 专利标题(中): 氰化羟基苯并噻唑化合物的生物发光检测
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申请号: US12556505申请日: 2009-09-09
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公开(公告)号: US20100075351A1公开(公告)日: 2010-03-25
- 发明人: Jessica Anderson , Poncho Meisenheimer , John Shultz , James J. Cali , Dongping Ma
- 申请人: Jessica Anderson , Poncho Meisenheimer , John Shultz , James J. Cali , Dongping Ma
- 申请人地址: US WI Madison
- 专利权人: Promega Corporation
- 当前专利权人: Promega Corporation
- 当前专利权人地址: US WI Madison
- 主分类号: C12Q1/66
- IPC分类号: C12Q1/66 ; C07K5/10
摘要:
The invention provides methods that employ derivatives of 2-cyano-6-hydroxy- or 2-cyano-6-amino-benzothiazole, for example, in a bioluminogenic reaction. Also provided are novel compounds that can be used in the methods. The invention further provides methods for detecting or determining the presence of molecules and/or enzymes, the modulator activity of such molecules, and/or the activity of such enzymes. The methods are adaptable to high-throughput format.