发明申请
- 专利标题： GRAM-POSITIVE CARBAPENEM ANTIBACTERIALS AND PROCESSES FOR THEIR PREPARATION
- 专利标题（中）： 碳酸氢钠抗菌素及其制备方法
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申请号： US12613795申请日： 2009-11-06
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公开(公告)号： US20100075945A1公开(公告)日： 2010-03-25
- 发明人: Woo-Baeg Choi , David S. Menaldino , Deog-II Kim , Martin Bouygues , Michael W. Hager
- 申请人： Woo-Baeg Choi , David S. Menaldino , Deog-II Kim , Martin Bouygues , Michael W. Hager
- 主分类号： A61K31/407
- IPC分类号： A61K31/407 ; C07D487/04 ; A61P31/00
摘要：
The present invention provides β-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment. The present invention is also in the field of synthetic organic chemistry and is specifically provides an improved method of synthesis of β-methyl carbapenems which are useful as antibacterial agents.
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